Associations of Osteoporosis, Sarcopenia, and Osteosarcopenia With Mortality: A Comparative Analysis for Different Sarcopenia Definitions in the Manitoba and NHANES Populations - PubMed
7 hours ago
- #osteoporosis
- #sarcopenia
- #mortality
- Osteosarcopenia, osteoporosis, and sarcopenia are significantly associated with increased mortality risk.
- The study analyzed data from the Manitoba Bone Mineral Density Database (MBMDD) and NHANES, involving 69,497 and 8,134 adults, respectively.
- Osteosarcopenia showed a stronger association with mortality compared to osteoporosis or sarcopenia alone.
- Five different definitions of sarcopenia were considered, including FNIH1, FNIH2, EWGSOP2, AWGS, and IWG.
- Mortality was higher in individuals with osteoporosis (HR: 1.26-1.31), sarcopenia (HR: 1.45-1.64), and osteosarcopenia (HR: 1.91-2.05).
- The study reinforces the public health concern of osteosarcopenia and its link to mortality.