Distinct Prescription Patterns Emerge Years Before ALS Diagnosis: A Nationwide Registry-Based Study - PubMed
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- #prodromal phase
- #ALS
- #prescription patterns
- Distinct prescription patterns emerge 2-3 years before ALS diagnosis.
- 25 out of 42 therapeutic drug classes were prescribed more frequently to ALS patients.
- Muscle relaxants and bone disease treatments were prescribed more frequently 6 and 5 years before diagnosis, respectively.
- The study suggests a prodromal phase of ALS lasting several years before clinical diagnosis.
- Increased medication use in the final year before diagnosis likely reflects heightened healthcare utilization.