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Highly efficient raw starch degradation by a novel dual-function maltogenic debranching enzyme of the intermediate GH13_20 subfamily from Deinococcus radiodurans - PubMed

8 hours ago
  • #starch-degradation
  • #biotechnology
  • #enzyme
  • A novel maltogenic debranching amylase (DrMD) from Deinococcus radiodurans was identified.
  • DrMD uniquely exhibits both pullulanase and maltogenic amylase activities at a single active site.
  • DrMD showed 4-fold higher efficiency in raw starch degradation compared to type I pullulanase.
  • The enzyme hydrolyzes the branch point of large amylopectin and cleaves the amylose structure.
  • DrMD effectively produces glucose (G1) and maltooligosaccharides (G2 to G5).
  • 86.97% of raw starch was degraded into low-molecular-weight glucans (<1 × 10^4 Da).
  • DrMD has potential as a versatile enzyme for industrial starch processing.