Effects of Radiotherapy in Normal Tissue - PubMed
3 hours ago
- #Normal Tissue Effects
- #Radiotherapy
- #Oncology
- Radiotherapy is a fundamental treatment in oncology, used across various cancer indications.
- Advances in imaging, treatment planning, and dose delivery have improved tumor control without increasing side effects.
- Modern radiotherapy allows for combined use with systemic therapies like targeted treatments and immunotherapies.
- Radiation-induced changes in normal tissue result from stem-cell senescence, inflammation, vascular changes, fibroblast activation, and loss of parenchymal cells.
- Research focuses on understanding the biology of radiation-induced tissue changes, biomarkers for side effects, and new treatment methods.
- Personalized approaches in radiotherapy aim to enhance efficacy and reduce side effects.