Alpha Oscillations and Conditioned Pain Modulation Is Associated With Treatment Resistance to Spinal Cord Stimulation for Neuropathic Pain - PubMed
5 hours ago
- #neuropathic pain
- #spinal cord stimulation
- #alpha oscillations
- Spinal cord stimulation (SCS) treatment resistance in neuropathic pain is linked to abnormal alpha oscillations and inefficient conditioned pain modulation (CPM).
- Pre-SCS testing showed that responders had lower alpha power in specific brain networks, while nonresponders exhibited abnormal CPM and reduced peak alpha frequency in the subgenual anterior cingulate cortex.
- These brain-behavioral measures may serve as predictive markers for SCS outcomes, aiding personalized pain management strategies.