HairTime: A noninvasive assay for estimating circadian phase from a single hair sample - PubMed
3 hours ago
- #biomarker
- #chronotherapy
- #circadian-rhythm
- HairTime is a noninvasive assay for estimating circadian phase from a single hair sample.
- Circadian phase is influenced by genetic and environmental factors and varies between individuals.
- Current gold standard for circadian phase assessment (DLMO) is impractical for large-scale studies.
- HairTime was developed and validated in two steps, showing strong predictive power compared to DLMO.
- The assay is suitable for large-scale studies, tested on over 4,000 samples.
- Circadian phase estimations showed associations with age, sex, and work schedules.
- HairTime lays the foundation for future applications in personalized chronotherapy.