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Comparative efficacy of GLP-1 RA, tirzepatide and SGLT-2 inhibitors in metabolic liver disease: A network meta-analysis - PubMed

5 days ago
  • #NAFLD
  • #SGLT-2 inhibitors
  • #GLP-1 RA
  • The study compares the efficacy of GLP-1 RAs, tirzepatide, and SGLT-2 inhibitors in treating metabolic liver diseases like NAFLD and NASH.
  • Exenatide and tirzepatide showed significant reductions in liver fat fraction and enzymes, outperforming other treatments like liraglutide and dapagliflozin.
  • The network meta-analysis included 25 studies with 2688 participants, highlighting the effectiveness of these drugs in improving NAFLD markers.