Prevention of Recurrent Nephrolithiasis in Adults and Children : A Systematic Review - PubMed
4 hours ago
- #kidney stones
- #prevention
- #nephrolithiasis
- Recurrent kidney stones can lead to serious complications like kidney damage and sepsis.
- The review assessed dietary, pharmacologic, and imaging strategies for preventing recurrent nephrolithiasis.
- Increased water intake, specific diets (normal-high calcium, low protein, low sodium), and medications (thiazides, alkali treatment, allopurinol) may reduce stone recurrence in adults (low strength of evidence).
- Acetohydroxamic acid may reduce stone growth in infection-related stones but has insufficient evidence on preventing recurrence and likely increases adverse events.
- Limited evidence exists on interventions for children, imaging strategies, and harms.
- Primary funding sources include the Patient-Centered Outcomes Research Institute and the Agency for Healthcare Research and Quality.