Hasty Briefsbeta

Bilingual

Targeted Delivery of Nucleic Acid Therapeutics: Emerging Carriers and Applications in Common Metabolic and Inflammatory Diseases - PubMed

4 hours ago
  • #nucleic acid therapeutics
  • #metabolic diseases
  • #drug delivery
  • Recent advances in genomics and molecular biology have accelerated nucleic acid-based therapeutics development.
  • Various delivery systems explored include lipid nanoparticles, polymeric nanomaterials, inorganic nanoparticles, extracellular vesicles, viral vectors, protein carriers, and nucleic acid conjugates.
  • The review focuses on classification, delivery strategies, and applications in metabolic and inflammatory diseases.
  • Emphasis is placed on mechanisms of action, targeted delivery approaches, and existing challenges.
  • Literature sourced from PubMed and Web of Science, focusing on relevance and recent publications (2020-2025).
  • Aims to provide insights for optimizing nucleic acid drugs and developing novel delivery systems.