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Molecular mechanisms and therapeutic potential of tryptophan metabolism in gut-brain signaling transduction: a narrative review - PubMed

7 hours ago
  • #Neuroprotection
  • #Gut-brain axis
  • #Tryptophan metabolism
  • The article reviews the molecular mechanisms and therapeutic potential of tryptophan metabolism in gut-brain signaling.
  • Key topics include the role of the aryl hydrocarbon receptor, gut microbiota, and the vagus nerve in the gut-brain axis.
  • Tryptophan metabolism is discussed in the context of health and disease, including its implications for neuroprotection and mental health.
  • References highlight the significance of tryptophan metabolites like quinolinic acid and kynurenic acid in brain function and pathology.
  • The authors declare no competing interests, and the study does not involve human participants or require ethical approval.