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Effectiveness and Safety of Topical Finasteride for Male Androgenetic Alopecia: Real World Data - PubMed

3 hours ago
  • #topical finasteride
  • #hair loss treatment
  • #androgenetic alopecia
  • Topical finasteride 0.25% monotherapy was evaluated for 52 weeks in 146 men with androgenetic alopecia (AGA).
  • Significant increases in target area hair count (TAHC) were observed at both vertex (+22.7 hairs/cm²) and frontotemporal regions (+32.3 hairs/cm²).
  • Improvements in target area hair width (TAHW) and terminal-to-vellus hair ratio were also noted in both regions.
  • Patient-reported outcomes (MHGQ score: 14.7 ± 2.9) and physician evaluations (PGA: +1.9 ± 0.8) indicated positive results.
  • Mild, transient local irritation occurred in 6.2% of patients, with no systemic adverse effects reported.
  • The study supports topical finasteride as an effective and safe long-term treatment for male AGA, particularly in frontotemporal regions.