Effect of liposomal bupivacaine thoracic paravertebral block on postoperative analgesia in patients undergoing video-assisted thoracoscopic surgery: a randomized controlled trial - PubMed
3 hours ago
- #Liposomal Bupivacaine
- #Postoperative Analgesia
- #VATS
- Study compares liposomal bupivacaine (LB) vs. bupivacaine with dexamethasone (BD) for postoperative analgesia in VATS patients.
- LB significantly prolonged analgesia duration (1160.4 min vs. 743.1 min, p<0.001) compared to BD.
- LB group showed lower NRS pain scores on the first postoperative day and reduced 72-hour pain scores.
- LB associated with lower opioid consumption, earlier ambulation/flatus, and higher patient satisfaction.
- No significant differences in intraoperative sufentanil use, hospital stay, or adverse events between groups.