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Overcoming functional and translational challenges of cellular immunotherapies for solid tumors - PubMed

3 hours ago
  • #immunotherapy
  • #solid tumors
  • #cellular therapy
  • Immunotherapy has revolutionized cancer treatment, offering new hope for patients.
  • Cell-based therapies, including engineered T cells, NK cells, and stem cells, show promise in leveraging immune cells to target cancer.
  • Despite success in hematologic malignancies, significant challenges remain in applying these therapies to solid tumors.
  • Key challenges include functional limitations and translational hurdles in clinical development.
  • Potential solutions involve innovative engineering, combination therapies, and emerging technologies to enhance efficacy.
  • Conflict of interest disclosures highlight industry ties among some authors.