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Interpretable machine learning models for stroke risk prediction in patients with newly diagnosed atrial fibrillation - PubMed

4 hours ago
  • #stroke prediction
  • #atrial fibrillation
  • #machine learning
  • Developed interpretable machine learning models (logistic regression and XGB) for 1-year stroke risk prediction in newly diagnosed atrial fibrillation patients.
  • Models used age, comorbidities, and medication data, achieving higher AUCs (0.877-0.915) than CHA₂DS₂-VASc (0.614-0.621) in internal and external validation.
  • Models showed strong calibration and clinical utility, with superior long-term risk stratification and treatment responsiveness to guide DOAC initiation.