Sex modulates the ventilatory response to passive limb-induced muscle mechanoreceptor activation during hypoxia in humans - PubMed
3 days ago
- #sex differences
- #respiratory physiology
- #hypoxia
- Sex influences the ventilatory response to passive limb movement during hypoxia, with males showing a greater response than females.
- The study involved 28 healthy adults (14 females) undergoing four experimental conditions to compare pulmonary ventilation responses.
- Males exhibited a synergistic interaction between the carotid chemoreflex and muscle mechanoreflex, which was not observed in females.
- Pulmonary ventilation remained elevated in males post-stimulation under hypoxia, suggesting short-term potentiation as a contributing mechanism.
- The findings highlight sex-specific differences in respiratory control mechanisms during hypoxic conditions.