Leishmania sand fly-transmission is disrupted by Delftia tsuruhatensis TC1 bacteria - PubMed
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- #Leishmania
- #sand fly
- #Delftia tsuruhatensis
- Delftia tsuruhatensis TC1 bacteria disrupts Leishmania sand fly-transmission.
- The bacteria colonizes the midgut of Phlebotomus duboscqi sand flies, impacting L. major parasite development indirectly via gut dysbiosis.
- Infected sand flies with D. tsuruhatensis show reduced L. major transmission and disease severity in mice.
- Modelling suggests potential disruption of leishmaniasis endemicity, positioning D. tsuruhatensis as a promising control agent.