Emergence of Carbapenem-Resistant Putative Hypervirulent Klebsiella pneumoniae ST147 with a Distinct Hybrid Plasmid in Türkiye - PubMed
10 hours ago
- #hybrid plasmids
- #Carbapenem resistance
- #ST147 clone
- CR-hvKp prevalence in Türkiye increased from 20.7% in 2018 to 33.1% by 2023.
- Dominant clone shifted from ST2096 (mainly blaOXA-232) before 2022 to ST147 (co-carrying blaNDM-5 and blaOXA-48, KL64 capsule).
- ST147 carries a 364-kb hybrid plasmid (pPF302_hybrid) with IncHI1B_pNDM and IncFIB_pNDM replicons, including novel resistance genes rmtF1 and arr-2.