Pulsed Field Versus Radiofrequency Ablation in Concomitant Pulmonary Vein Isolation and LAA Occlusion: Impact on Peridevice Leak and Procedural Efficiency - PubMed
3 hours ago
- #left atrial appendage occlusion
- #pulsed field ablation
- #atrial fibrillation
- Comparison of pulsed field ablation (PFA) and radiofrequency ablation (RFA) in concomitant pulmonary vein isolation (PVI) and left atrial appendage occlusion (LAAO).
- PFA associated with lower peridevice leak (PDL) rates (5.1%) compared to RFA (23%) at 45-day follow-up.
- Mean procedure duration significantly shorter with PFA + LAAO (67.1 min) vs. RFA + LAAO (99.6 min).
- No large PDL (>5 mm) observed; small PDL (≤5 mm) more common in RFA group.
- Safety outcomes comparable across groups with rare major complications and device-related thrombosis.
- Study suggests PFA + LAAO improves procedural efficiency and reduces PDL without compromising safety.