Immunity in Alzheimer's disease: From mechanisms to therapies - PubMed
3 hours ago
- #Alzheimer's disease
- #neuroimmunology
- #microglia
- Alzheimer's disease (AD) is a progressive neurodegenerative disorder leading to cognitive decline and dementia.
- Recent discoveries highlight the role of neuroimmune interactions in AD development and progression.
- Innate and adaptive immunity, including microglia and T cells, contribute to AD pathogenesis.
- Genetic risk factors converge on microglial activation and antigen presentation pathways.
- Microglia and T cells have both protective and pathogenic roles at different AD stages.
- Emerging therapies aim to modulate neuroimmune dynamics precisely during AD progression.