Nutrients and bioactive compounds in polycystic ovary syndrome: updated insights into effects and underlying mechanisms - PubMed
4 hours ago
- #PCOS
- #bioactive compounds
- #nutrition
- Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder in women of reproductive age.
- PCOS management focuses on symptom control due to its complex and heterogeneous nature.
- Nutritional deficiencies in vitamins and minerals are common in PCOS and linked to insulin resistance and endocrine disturbances.
- Specific vitamins (E, K, D, B-8, B-9, B-12) and minerals (selenium, chromium, zinc, calcium, magnesium) may help manage PCOS symptoms.
- Bioactive compounds like melatonin, omega-3 fatty acids, coenzyme Q10, and N-acetylcysteine show potential in improving PCOS manifestations.
- Mechanisms include regulating glucose/lipid metabolism, hormonal balance, reducing oxidative stress, inflammation, and modulating gut microbiota.
- The review highlights integrative management approaches and future research directions for PCOS.