Global burden of adverse effects of medical treatment from 1990 to 2021: a Global Burden of Disease Study 2021 - PubMed
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- #Adverse effects of medical treatment
- #Global Burden of Disease
- #Healthcare overutilization
- Study evaluates global burden of adverse effects of medical treatment (AEMT) from 1990 to 2021 using Global Burden of Disease Study (GBD) 2021 data.
- AEMT includes complications from medical procedures, treatments, or healthcare exposures, categorized into fatal and non-fatal outcomes.
- In 2021, global age-standardized prevalence, incidence, DALYs, and mortality rates of AEMT were 11.48, 150.44, 64.19, and 1.53 per 100,000 population, respectively.
- DALY rates were highest in the early neonatal group (4,789.47 per 100,000 population).
- Mortality rates followed a U-shaped pattern across age groups, highest in early neonatal and 95+ age groups.
- Mortality-incidence ratios (MIRs) were highest in lower Socio-demographic Index (SDI) quintiles.
- Higher prevalence and incidence rates of AEMT in older populations in high SDI quintiles may be due to healthcare overutilization.
- Study highlights the need for policy adjustments to address AEMT burden.