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Enhanced predictive performance of artificial intelligence in individualized ovarian stimulation of in vitro fertilization: a retrospective cohort study - PubMed

a day ago
  • #In Vitro Fertilization
  • #Personalized Medicine
  • #Artificial Intelligence
  • Study investigates AI models for improving IVF success through controlled ovarian stimulation (COS).
  • Over 2.5 million IVF cycles are conducted annually, with numbers expected to rise.
  • AI models outperformed traditional clinical practices in predictive accuracy for COS optimization.
  • A four-submodel system was developed, showing superior discrimination compared to conventional methods.
  • Key COS components impacting response include protocol, recombinant FSH use, and starting dose.
  • New potential biomarkers were identified for low and hyper ovarian responses.
  • AI system demonstrated high precision in identifying effective COS strategies (95.5% and 98.4%).
  • The study offers new insights for personalized reproductive medicine and IVF optimization.