Differences in distant metastasis risk of breast cancer originating from various primary sites: a retrospective analysis based on the SEER database - PubMed
3 hours ago
- #Distant Metastasis
- #SEER Database
- #Breast Cancer
- Breast cancer's primary site diversity influences distant metastasis patterns and patient survival.
- Study includes 240,943 female breast cancer patients from SEER data (2010-2019).
- Primary sites classified into UIQ, LIQ, UOQ, LOQ, axillary tail, overlapping region, and TCNP.
- Distant metastatic organs include bone, brain, liver, and lung.
- Axillary tail tumors have higher risk of bone and lung metastasis compared to UOQ.
- UIQ tumors linked to lower risk of bone metastasis; TCNP has higher risk of bone and liver metastasis.
- Brain metastasis indicates poorer prognosis than bone metastasis.
- Primary site impact on survival less significant when metastasis occurs in the same organ.
- Findings may help focus preventive measures on susceptible organs early in diagnosis.