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Dynamics of salivary stress-related biomarkers in children with malocclusion and risk for sleep problems and sleep-disordered breathing: a cross-sectional study - PubMed

a day ago
  • #salivary-biomarkers
  • #sleep-disordered-breathing
  • #malocclusion
  • Study examines salivary stress-related biomarkers in children with malocclusion at risk for sleep problems and sleep-disordered breathing (SDB).
  • 75 children aged 7-12 years were assessed using the Japanese Sleep Questionnaire for Elementary Schoolers (JSQ-ES).
  • High-risk groups identified: 18.7% for general sleep problems and 50.7% for SDB.
  • Lower oxytocin levels found in high-risk sleep problems group, negatively correlating with JSQ-ES scores.
  • No biomarker differences observed in SDB risk groups.
  • High-risk sleep problems group showed greater mandibular plane angle.
  • Higher SDB scores associated with anteroposterior skeletal discrepancies.
  • Findings suggest reduced oxytocin and vertical skeletal divergence in sleep problem risks, and craniofacial differences in SDB risks without biomarker changes.