The evolving comorbidity landscape of rheumatoid arthritis - PubMed
3 hours ago
- #rheumatoid arthritis
- #healthcare
- #comorbidity
- Rheumatoid arthritis (RA) is linked to various comorbidities that significantly impact quality of life and long-term health outcomes.
- Comorbidities include extra-articular manifestations, cardiovascular disease, cerebrovascular accidents, dementia, malignancy, infection, mental health disorders, and osteoporosis.
- Comorbidity patterns have shifted over the past three decades, with declining prevalence of some complications but persistently high or increasing burdens of interstitial lung disease, anxiety, and depression.
- Changes in the comorbidity landscape likely result from advances in RA management, such as increased use of biologic and targeted synthetic DMARDs and the adoption of treat-to-target strategies.
- Clinical care is increasingly focused on comorbidity-specific epidemiology, the effects of DMARDs on comorbidity risk, and integrated approaches to address both RA and comorbid diseases.
- Preventive strategies, including enhanced screening for conditions like cervical cancer, interstitial lung disease, cardiovascular disease, and osteoporosis, are crucial components of comprehensive RA management.
- Awareness of evolving comorbidity trends supports more integrated and individualized care for people with RA.