Global and regional prevalence, burden, and risk factors for MASLD in children and adolescents aged 5 to 24 years: a systematic review, meta-analysis, and modeling study - PubMed
4 hours ago
- #childhood obesity
- #global health
- #MASLD
- Study focuses on estimating the prevalence, burden, and risk factors of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in children and adolescents aged 5-24 years.
- Systematic review and meta-analysis conducted using data from multiple databases including PubMed, EMBASE, and CNKI.
- Global MASLD prevalence among 5-24-year-olds was found to be 7.0%, increasing with age and higher in boys.
- Asia had the highest number of MASLD cases in 2000 and 2020, but Africa is projected to surpass Asia by 2040.
- In China, highest MASLD prevalence was observed in Hebei, Shandong, and Beijing in 2000, shifting to Tianjin, Shandong, and Heilongjiang from 2020 onwards.
- Rising obesity rates are linked to increasing MASLD prevalence, necessitating targeted obesity prevention and health services.
- Study highlights the need for investment in health services to mitigate the long-term impacts of MASLD.