Prevascularized Bone Marrow-Derived Mesenchymal Stem Cell Sheets Promote Tendon-Bone Integration in Rotator Cuff Repair - PubMed
7 hours ago
- #tendon-bone integration
- #mesenchymal stem cells
- #rotator cuff repair
- Prevascularized BMSC sheets enhance tendon-bone integration in rotator cuff repair.
- Study involved 20 rabbits with BMSC sheets or prevascularized BMSC sheets implanted at the tendon-bone interface.
- Prevascularized sheets showed improved vascularization, collagen type II alpha 1, and interleukin 10 levels.
- Biomechanical tests revealed higher ultimate failure load and stiffness with prevascularized sheets.
- Clinical relevance suggests prevascularized BMSC sheets as a biologic adjunct for better rotator cuff healing.