Hashimoto's thyroiditis: from pathogenesis to clinical management - PubMed
3 days ago
- #autoimmunity
- #Hashimoto’s thyroiditis
- #hypothyroidism
- Hashimoto's thyroiditis (HT) is a chronic autoimmune thyroiditis leading to hypothyroidism in iodine-sufficient regions.
- HT is more prevalent in adult women, about four times more common than in men.
- Pathogenesis involves genetic susceptibility, environmental factors, and immune regulation.
- Diagnosis relies on serological tests (TPOAb/TGAb) and thyroid ultrasound features.
- Current treatment is levothyroxine (T4) replacement therapy.
- The article reviews HT's pathogenesis, current treatment status, and challenges.