Pharmacological and non-pharmacological management of long COVID - PubMed
3 hours ago
- #Post-COVID syndrome
- #Probiotics
- #Long COVID
- Long COVID affects approximately 10% of COVID-19 patients, leading to autonomic dysfunction, cardiovascular complications, and neurological impairments.
- The exact mechanisms of Long COVID are unclear but may involve immune dysregulation, persistent viral reservoirs, chronic inflammation, gut dysbiosis, and vascular dysfunction.
- Non-pharmacological interventions like increased salt intake, elimination diets, and cognitive pacing may help but are insufficient for severe symptoms.
- Pharmacological treatments such as β-blockers, calcium channel blockers, pyridostigmine, antihistamines, and low-dose naltrexone can improve symptoms like tachycardia, fatigue, and brain fog, but standardized guidelines are lacking.
- Probiotics, including Bacillus coagulans, Bacillus subtilis, Lactobacillus acidophilus, and Bifidobacterium species, show promise in improving fatigue, gastrointestinal health, and overall well-being in Long COVID patients.
- Large-scale randomized controlled trials are needed to validate the efficacy of probiotics in Long COVID management.