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The sialic shield of leukemia cells - PubMed

4 hours ago
  • #sialic acid
  • #immune evasion
  • #leukemia
  • Sialylated proteins form a protective coat on leukemia cells.
  • This sialic shield inhibits antileukemic immune responses.
  • The research focuses on sialylated CD43 as a glyco-immune barrier.
  • The study was published in Science in 2026.
  • Findings highlight a mechanism that leukemia cells use to evade immune destruction.