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Timing-dependent effects of melatonin supplementation on exercise performance and exercise-induced muscle damage: a systematic review and meta-analysis - PubMed

4 hours ago
  • #melatonin
  • #muscle damage
  • #exercise performance
  • Melatonin supplementation has timing-dependent effects on exercise performance and muscle damage.
  • Evening administration with >6-h intervals before exercise enhances endurance and explosive power.
  • Higher doses (6-10 mg) and athlete populations show greater performance improvements.
  • Melatonin significantly reduces creatine kinase levels, indicating reduced muscle damage.
  • Adolescents (≤18 years) experience enhanced explosive power responses to melatonin.