Cardiometabolic prediction models for young people with psychosis spectrum disorders in the UK (PsyMetRiC 2.0): a retrospective, multicohort clinical prediction model study - PubMed
3 hours ago
- #psychosis
- #cardiometabolic
- #prediction models
- Study focuses on developing cardiometabolic prediction models (PsyMetRiC 2.0) for young people with psychosis spectrum disorders in the UK.
- Aims to refine and validate models for metabolic syndrome, type 2 diabetes, and significant weight gain using primary and secondary care datasets.
- Includes 25,850 individuals, with models showing good discriminative performance (C-statistics ranging from 0.77 to 0.86).
- Models incorporate new predictors like family history of cardiometabolic disorders, antidepressant prescriptions, and biochemical markers.
- PsyMetRiC web application developed for clinical use, supporting preventive physical health care in young people with psychosis.
- Funded by the National Institute for Health and Care Research, with models available under the CC BY 4.0 license.