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Definitions of early COPD and predictors for disease progression: a systematic review - PubMed

a day ago
  • #COPD
  • #systematic review
  • #disease progression
  • Early COPD lacks standardized definitions, hindering research and clinical application.
  • Systematic review analyzed 4871 articles, identifying terms like PRISm, GOLD 0, early COPD, at-risk COPD, and pre-COPD.
  • Definitions of early COPD were heterogeneous and not routinely used.
  • Predictors of disease progression include age, smoking history, symptoms, exacerbations, lung function measures, CT metrics, risk tools, and machine learning.
  • Consensus on early COPD definitions is urgently needed to improve patient outcomes.