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Herpesvirus genome integration in whole-genome sequences of dementia and control cohorts - PubMed

3 hours ago
  • #herpesvirus
  • #neurodegenerative
  • #dementia
  • Study investigates herpesvirus genome integration in dementia and control cohorts.
  • Over 7500 whole-genome sequences analyzed using PathSeq tool.
  • Higher prevalence of partial HHV-6 integration in synucleinopathies (LBD and MSA).
  • Suggests potential role of HHV-6 integration in subsets of dementia patients.
  • No significant integration noted for other herpesviruses in these cohorts.