Fertility, pregnancy and lactation in women with systemic lupus erythematosus - PubMed
3 hours ago
- #fertility management
- #pregnancy complications
- #systemic lupus erythematosus
- SLE predominantly affects women of childbearing age, and pregnancy rates are increasing due to improved survival and quality of life.
- Pregnancy in SLE carries higher risks of maternal complications and adverse fetal outcomes compared to the general population.
- Risk factors for complications include active disease at conception, history of lupus nephritis, antiphospholipid syndrome, or recent medication withdrawal.
- Preconception counseling, risk assessment, pregnancy planning, medication adjustment, and multidisciplinary management are crucial for improving outcomes.
- Knowledge gaps remain regarding mechanisms of complications and treatment safety during conception, pregnancy, and lactation.