Endothelial activation and stress index (EASIX) as a predictor of acute kidney injury in patients undergoing transcatheter aortic valve replacement: A retrospective cohort study - PubMed
4 days ago
- #TAVR
- #acute kidney injury
- #EASIX
- EASIX (Endothelial Activation and Stress Index) is explored as a predictor for acute kidney injury (AKI) post-TAVR.
- The study retrospectively analyzed 130 patients undergoing TAVR, with 15.4% developing contrast-induced nephropathy (CIN).
- Baseline EASIX was significantly higher in patients who developed CIN compared to those who did not (2.92 vs 1.33, P < .001).
- An EASIX threshold of ≥1.904 predicted CIN with high sensitivity (90.3%) and specificity (86.2%).
- Multivariable analysis confirmed EASIX, contrast volume, and baseline eGFR as independent predictors of CIN.
- EASIX is highlighted as a practical tool for pre-procedural risk stratification in TAVR patients.