Single-cell transcriptomic profiling of human fetal neural stem cells isolated from the subventricular zone - PubMed
3 hours ago
- #regenerative medicine
- #transcriptomics
- #neural stem cells
- Single-cell transcriptomic profiling of human fetal neural stem cells (hNSCs) from the subventricular zone (SVZ) was conducted.
- Analysis revealed sub-populations including neural progenitor cells expressing quiescent markers and clusters diverging toward glial and neuronal lineages.
- Extended in vitro culture induced a progressive transcriptional shift toward differentiation, but late-passage hNSCs retained stemness, showing long-term stability.