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GLP-1 receptor agonists for weight loss: A systematic review and meta-analysis of randomized controlled trials - PubMed

7 hours ago
  • #weight loss
  • #GLP-1 agonists
  • #obesity
  • GLP-1 receptor agonists significantly increase the likelihood of weight loss compared to placebo.
  • Tirzepatide and semaglutide ranked highest in efficacy among GLP-1-based agents.
  • The study analyzed 21 randomized controlled trials involving 7024 participants.
  • 78.54% of participants on GLP-1 agents achieved weight loss vs. 26.53% on placebo.
  • The findings support GLP-1-based therapy as effective for clinical obesity management.