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Candida meningitis in three patients who underwent transsphenoidal surgery from a single-institution case series - PubMed

4 hours ago
  • #Transsphenoidal surgery
  • #Candida meningitis
  • #Neurosurgical complications
  • Candida meningitis is a rare but potentially deadly complication in neurosurgical patients.
  • Three cases of Candida meningitis were identified in patients who underwent transsphenoidal surgery at Karolinska University Hospital.
  • All three patients had postoperative CSF rhinorrhea and underwent endonasal endoscopic CSF leak repair surgery.
  • Patients were treated with Amphotericin B and Fluconazole successfully.
  • Risk factors include large central tumors, postoperative CSF leakage, and prolonged cortisone use.
  • Candida meningitis can occur even in previously healthy individuals, not just immunocompromised patients.