Spontaneous aging-associated inflammation and genome instability in the immune system of turquoise killifish - PubMed
3 hours ago
- #aging
- #immune system
- #turquoise killifish
- Turquoise killifish (Nothobranchius furzeri) are short-lived vertebrates that model human aging.
- Old killifish show increased inflammation markers and DNA damage in immune cell progenitors.
- Single-cell RNA sequencing and proteomic profiling reveal age-related immune system changes.
- Killifish exhibit rapid immune system aging within less than 10 weeks.
- The study highlights killifish as a model for immune-system-targeted antiaging interventions.