Life-Course Social Mobility and Cardiometabolic Disease: Evidence from Five International Cohorts - PubMed
4 hours ago
- #Social Determinants of Health
- #Life Course Epidemiology
- #Cardiometabolic Disease
- Study investigates life-course social determinants of health (SDOH) and social mobility associations with cardiometabolic disease (CMD) risk.
- Low SDOH in childhood, early adulthood, middle-late adulthood, and cumulative across life course linked to higher CMD risks.
- Adverse social mobility trajectories (stable low, downward, increase-then-decline) also associated with elevated CMD risk.
- Lifestyle and psychosocial factors explain 13.3%-50.5% and 15.8%-73.7% of these associations, respectively, with greatest attenuation for heart diseases.
- Maintaining healthy lifestyles and favorable psychosocial well-being may mitigate CMD risk, especially in synergy with cumulative SDOH.