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Non-linear association between cardiometabolic index and helicobacter pylori infection: a cross-sectional study - PubMed

2 days ago
  • #Cardiometabolic index
  • #Helicobacter pylori
  • #NHANES
  • The study explores the non-linear association between the cardiometabolic index (CMI) and Helicobacter pylori (H. pylori) infection.
  • Data from the NHANES 1999-2000 survey was used, involving 3357 participants with complete H. pylori serology and CMI data.
  • Higher CMI levels were linked to increased odds of H. pylori infection, with a 21% higher odds per standard deviation increase in CMI.
  • A non-linear relationship was identified with an inflection point at CMI ≈ 2.8; below this point, CMI increases significantly raised infection risk, but not above it.
  • Subgroup analyses showed no significant differences in the association across different populations.
  • The study suggests future research should validate these findings in contemporary, longitudinal cohorts.