MASLD as a systemic metabolic disease: expanding the scope of cardiovascular-kidney-metabolic (CKM) syndrome - PubMed
3 hours ago
- #multidisciplinary care
- #CKM syndrome
- #MASLD
- MASLD is a prevalent liver condition with systemic cardiometabolic impacts.
- MASLD increases cardiovascular and renal risks through mechanisms like insulin resistance and inflammation.
- Current CKM syndrome framework excludes MASLD, suggesting a need for an expanded CKLM model.
- Early identification and multidisciplinary care are crucial for managing MASLD.
- Pharmacotherapies like GLP-1 receptor agonists and SGLT2 inhibitors show cross-organ benefits.
- Integrating MASLD into CKLM could improve clinical outcomes and address multimorbidity.