Trajectory pattern of serum urea nitrogen to creatinine ratio in acute kidney injury requiring continuous renal replacement therapy: A post hoc analysis of a retrospective multicenter cohort study - P
3 hours ago
- #continuous renal replacement therapy
- #acute kidney injury
- #mortality
- Study investigates the association between laboratory data phenotypes and mortality in AKI patients undergoing CRRT.
- Patients were categorized into three groups based on lactate levels and serum urea nitrogen-to-creatinine ratio (UCR).
- Groups with high lactate or high UCR showed higher mortality rates compared to the group with normal levels.
- External validation using MIMIC-IV database confirmed the study findings.
- UCR may reflect increased protein metabolism and serve as a useful mortality risk factor in severe AKI patients requiring CRRT.