Predictive biomarkers of response to chimeric antigen receptor (CAR) T-cell therapy for pan-haematologic cancer - PubMed
3 days ago
- #CAR T-cell therapy
- #predictive biomarkers
- #haematologic cancer
- Study focuses on predictive biomarkers for CAR T-cell therapy response in pan-haematologic cancer.
- Analyzed 256 patients across 5 cancer types and 13 clinical trials.
- Data framework includes pre-infusion clinical features, T-cell analysis, serum markers, and CAR T-cell tracking.
- Identifies potential pan-cancer biomarkers for treatment response and non-response.
- Multiple authors have conflicts of interest, including patents, equity, and consultancy roles in biotech firms.