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Clinical Practice Guidelines for Biliary Atresia in Japan, 2nd Edition - PubMed

3 hours ago
  • #biliary atresia
  • #clinical guidelines
  • #MINDS
  • The study revised the clinical practice guidelines for biliary atresia (BA) in Japan, following the MINDS Handbook for Clinical Practice Guideline Development 2020 ver.3.0.
  • 23 clinical questions (CQs) were identified, with recommendations provided for 22 CQs. No recommendation was made for CQ12 (laparoscopic surgery) due to limited evidence.
  • The guidelines were developed through systematic literature searches, evidence synthesis, and structured consensus methods using the modified Delphi technique.
  • Recommendations were graded based on the strength of evidence and the clinical balance of benefits and harms.
  • The second edition of the guidelines aims to standardize BA management and improve treatment outcomes.
  • Key references include works by M. Kasai, T.E. Starzl, and the Japanese Biliary Atresia Society.