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Urological manifestations in familial mediterranean fever excluding renal amyloidosis: a systematic review - PubMed

4 hours ago
  • #Infertility
  • #Urological Manifestations
  • #Familial Mediterranean Fever
  • Systematic review of urological manifestations in Familial Mediterranean Fever (FMF), excluding renal amyloidosis.
  • Analysis included 38 studies (2,040 patients) with mean age 23.35±16 years; 43.2% female.
  • Most common urological manifestations: acute scrotum (n=64, 75% recurrence), epididymo-orchitis (n=25, 84% with fever), testicular amyloidosis (n=40).
  • Other findings: testicular torsion (n=4), hydrocele (n=4), bladder amyloidosis (n=2).
  • Semen analysis (n=189) showed azoospermia (26.9%) and oligospermia (14.8%); infertility linked to testicular amyloidosis.
  • Highlights the need to consider urological involvement in FMF clinical practice.