Slowed Gompertzian ageing in long-lived C. elegans results from expansion of decrepitude, not decelerated ageing - PubMed
5 hours ago
- #C. elegans
- #ageing research
- #mortality analysis
- Slowed Gompertzian ageing in long-lived C. elegans is characterized by expansion of decrepitude (gerospan), not a slower biological ageing rate.
- The Gompertz parameter β reflects decrepitude expansion in longer-lived individuals, while α reductions are linked to healthspan expansion and slowed biological ageing.
- Interventions extending lifespan can impact α (ageing-independent mortality) and β (mortality rate increase), redefining traditional interpretations of these parameters.