A clinical review of cervical cancer - PubMed

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Cervical cancer is the fourth most common cancer in females globally, with 600,000 new cases and 350,000 deaths in 2022.
In the U.S., projections for 2025 include 13,360 new diagnoses and 4,320 deaths, with most patients aged 35-44 at diagnosis.
Higher incidence and mortality are observed among Black, Latina, Hispanic, American Indian, and Alaska Native females, particularly in lower-income countries due to screening and treatment access inequalities.
Key risk factors include human papillomavirus (HPV) infection, and public health priorities focus on risk reduction, early recognition, and prompt treatment.
Diagnosis involves methods like the Papanicolaou test and colposcopy, while management includes chemotherapy, hysterectomy, and targeted therapy, with vaccination as a preventive measure.

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