Perilesional neuromodulation replaces lost sensorimotor function in persons with spinal cord injury - PubMed
7 hours ago
- #neuromodulation
- #sensorimotor function
- #spinal cord injury
- Perilesional neuromodulation restores sensorimotor function in spinal cord injury (SCI) patients.
- Epidural electrical stimulation (EES) below the lesion can restore movement and autonomic function but not sensation.
- First-in-human results show perilesional EES enables motor activation and somatosensory feedback in chronic SCI patients.
- Deep learning and participant-directed control help determine motor- and sensory-specific EES parameters.
- Supralesional EES synchronizes sensations with leg movement, improving leg position awareness.
- Simultaneous supralesional and sublesional EES allows intentional control and sensory feedback during functional tasks.
- This approach may enhance quality of life for individuals with SCI.